Parametric Probability Distribution Functions for Axon Diameters of Corpus Callosum
نویسندگان
چکیده
منابع مشابه
Parametric Probability Distribution Functions for Axon Diameters of Corpus Callosum
Axon diameter is an important neuroanatomical characteristic of the nervous system that alters in the course of neurological disorders such as multiple sclerosis. Axon diameters vary, even within a fiber bundle, and are not normally distributed. An accurate distribution function is therefore beneficial, either to describe axon diameters that are obtained from a direct measurement technique (e.g...
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Here, we present the first in vivo non-invasive measurement of the axon diameter distribution in the rat corpus callosum. Previously, this measurement was only possible using invasive histological methods. The axon diameter, along with other physical properties, such as the intra-axonal resistance, membrane resistance and capacitance etc. helps determine many important functional properties of ...
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Introduction The axon diameter distribution (ADD) is an important anatomical feature of nerve fascicles both in normal and abnormal development. It is well known that the nerve conduction velocity is directly proportional to axon diameter in myelinated axons. Generally, large-diameter axons arise in pathways that require short conduction times while smaller axons are found in pathways that can ...
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Knowledge of microstructural features of nerve fascicles, such as their axon diameter, is crucial for understanding normal function in the central and peripheral nervous systems as well as assessing changes due to pathologies. In this study double-pulsed field gradient (d-PFG) filtered MRI was used to map the average axon diameter (AAD) in porcine spinal cord, which was then compared to AADs me...
متن کاملAxon position within the corpus callosum determines contralateral cortical projection.
How developing axons in the corpus callosum (CC) achieve their homotopic projection to the contralateral cortex remains unclear. We found that axonal position within the CC plays a critical role in this projection. Labeling of nearby callosal axons in mice showed that callosal axons were segregated in an orderly fashion, with those from more medial cerebral cortex located more dorsally and subs...
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ژورنال
عنوان ژورنال: Frontiers in Neuroanatomy
سال: 2016
ISSN: 1662-5129
DOI: 10.3389/fnana.2016.00059